{
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  "Type": "Package",
  "Package": "chevron",
  "Title": "Standard TLGs for Clinical Trials Reporting",
  "Version": "0.2.12.91",
  "Date": "2026-01-14",
  "Authors@R": "c(\nperson(\"Liming\", \"Li\", , \"liming.li@roche.com\", role = \"aut\",\ncomment = c(ORCID = \"0009-0008-6870-0878\", \"Original creator of the package\")),\nperson(\"Benoit\", \"Falquet\", , \"benoit.falquet@roche.com\", role = \"aut\",\ncomment = c(ORCID = \"0000-0002-4434-3799\", \"Original creator of the package\")),\nperson(\"Xiaoli\", \"Duan\", , \"xiaoli.duan@roche.com\", role = \"aut\"),\nperson(\"Adrian\", \"Waddell\", , \"adrian.waddell@gmail.com\", role = \"ctb\"),\nperson(\"Chenkai\", \"Lv\", , \"chenkai.lv@roche.com\", role = \"ctb\"),\nperson(\"Pawel\", \"Rucki\", , \"pawel.rucki@roche.com\", role = \"ctb\"),\nperson(\"Tim\", \"Barnett\", , \"timothy.barnett@roche.com\", role = \"ctb\"),\nperson(\"Tian\", \"Fang\", , \"tian.fang@roche.com\", role = \"ctb\"),\nperson(\"Joe\", \"Zhu\", , \"joe.zhu@roche.com\", role = \"cre\",\ncomment = c(ORCID = \"0000-0001-7566-2787\")),\nperson(\"F. Hoffmann-La Roche AG\", role = c(\"cph\", \"fnd\"))\n)",
  "Description": "Provide standard tables, listings, and graphs (TLGs)\nlibraries used in clinical trials. This package implements a\nstructure to reformat the data with 'dunlin', create reporting\ntables using 'rtables' and 'tern' with standardized input\narguments to enable quick generation of standard outputs.  In\naddition, it also provides comprehensive data checks and script\ngeneration functionality.",
  "License": "Apache License 2.0",
  "URL": "https://insightsengineering.github.io/chevron/,\nhttps://github.com/insightsengineering/chevron/",
  "BugReports": "https://github.com/insightsengineering/chevron/issues",
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  "Config/pak/sysreqs": "cmake make libicu-dev",
  "Repository": "https://insightsengineering.r-universe.dev",
  "Date/Publication": "2026-01-14 15:22:20 UTC",
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    "rmpt04",
    "rmpt04_main",
    "rmpt04_pre",
    "rmpt05",
    "rmpt05_main",
    "rmpt05_pre",
    "rmpt06",
    "rmpt06_main",
    "rmpt06_post",
    "rmpt06_pre",
    "rspt01",
    "rspt01_main",
    "rspt01_post",
    "rspt01_pre",
    "run",
    "script_funs",
    "set_section_div",
    "standard_null_report",
    "std_postprocessing",
    "ttet01",
    "ttet01_main",
    "ttet01_post",
    "ttet01_pre",
    "unwrap_layout",
    "var_labels_for",
    "vst01",
    "vst01_main",
    "vst01_pre",
    "vst02_1",
    "vst02_1_main",
    "vst02_2",
    "vst02_2_main",
    "vst02_post",
    "vst02_pre",
    "with_label",
    "yes_no_rule"
  ],
  "_datasets": [
    {
      "name": "ctcv4_dir",
      "title": "CTC version 4 Grade Direction Data",
      "object": "ctcv4_dir",
      "class": [
        "data.frame"
      ],
      "fields": [
        "PARAMCD",
        "GRADE_DIR",
        "CTCv"
      ],
      "rows": 35,
      "table": true,
      "tojson": true
    },
    {
      "name": "ctcv5_dir",
      "title": "CTC version 5 Grade Direction Data",
      "object": "ctcv5_dir",
      "class": [
        "data.frame"
      ],
      "fields": [
        "PARAMCD",
        "GRADE_DIR",
        "CTCv"
      ],
      "rows": 35,
      "table": true,
      "tojson": true
    },
    {
      "name": "mla_dir",
      "title": "MLA Grade Direction Data",
      "object": "mla_dir",
      "class": [
        "data.frame"
      ],
      "fields": [
        "PARAMCD",
        "GRADE_DIR"
      ],
      "rows": 76,
      "table": true,
      "tojson": true
    },
    {
      "name": "syn_data",
      "title": "Example 'adam' Synthetic Data",
      "object": "syn_data",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "chevron-package",
      "title": "'chevron' package",
      "topics": [
        "chevron-package",
        "chevron"
      ]
    },
    {
      "page": "ael01_nollt",
      "title": "'AEL01_NOLLT' Listing 1 (Default) Glossary of Preferred Terms and Investigator-Specified Terms.",
      "topics": [
        "ael01_nollt",
        "ael01_nollt_main",
        "ael01_nollt_pre"
      ]
    },
    {
      "page": "ael02",
      "title": "'AEL02' Listing 1 (Default) Listing of Adverse Events.",
      "topics": [
        "ael02",
        "ael02_main",
        "ael02_pre"
      ]
    },
    {
      "page": "ael03",
      "title": "'AEL03' Listing 1 (Default) Listing of Serious Adverse Events.",
      "topics": [
        "ael03",
        "ael03_main",
        "ael03_pre"
      ]
    },
    {
      "page": "aet01_aesi",
      "title": "'AET01_AESI' Table 1 (Default) Adverse Event of Special Interest Summary Table.",
      "topics": [
        "aet01_aesi",
        "aet01_aesi_main",
        "aet01_aesi_post",
        "aet01_aesi_pre"
      ]
    },
    {
      "page": "aet01",
      "title": "'AET01' Table 1 (Default) Overview of Deaths and Adverse Events Summary Table 1.",
      "topics": [
        "aet01",
        "aet01_main",
        "aet01_post",
        "aet01_pre"
      ]
    },
    {
      "page": "aet02",
      "title": "'AET02' Table 1 (Default) Adverse Events by System Organ Class and Preferred Term Table 1.",
      "topics": [
        "aet02",
        "aet02_label",
        "aet02_main",
        "aet02_post",
        "aet02_pre"
      ]
    },
    {
      "page": "aet03",
      "title": "'AET03' Table 1 (Default) Advert Events by Greatest Intensity Table 1.",
      "topics": [
        "aet03",
        "aet03_main",
        "aet03_post",
        "aet03_pre"
      ]
    },
    {
      "page": "aet04",
      "title": "'AET04' Table 1 (Default) Adverse Events by Highest 'NCI' 'CTACAE' 'AE' Grade Table 1.",
      "topics": [
        "aet04",
        "aet04_main",
        "aet04_post",
        "aet04_pre"
      ]
    },
    {
      "page": "aet05_all",
      "title": "'AET05_ALL' Table 1 (Default) Adverse Event Rate Adjusted for Patient-Years at Risk - All Occurrences.",
      "topics": [
        "aet05_all",
        "aet05_all_pre"
      ]
    },
    {
      "page": "aet05",
      "title": "'AET05' Table 1 (Default) Adverse Event Rate Adjusted for Patient-Years at Risk - First Occurrence.",
      "topics": [
        "aet05",
        "aet05_main",
        "aet05_post",
        "aet05_pre"
      ]
    },
    {
      "page": "aet10",
      "title": "'AET10' Table 1 (Default) Most Common (xx%) Adverse Events Preferred Terms Table 1.",
      "topics": [
        "aet10",
        "aet10_main",
        "aet10_post",
        "aet10_pre"
      ]
    },
    {
      "page": "args_ls",
      "title": "Get Arguments List",
      "topics": [
        "args_ls",
        "args_ls,chevron_tlg-method"
      ]
    },
    {
      "page": "assert_single_value",
      "title": "Check variable only has one unique value.",
      "topics": [
        "assert_single_value"
      ]
    },
    {
      "page": "assert_valid_type",
      "title": "Check variable is of correct type",
      "topics": [
        "assert_valid_type"
      ]
    },
    {
      "page": "assert_valid_var",
      "title": "Check whether var is valid",
      "topics": [
        "assert_valid_var",
        "assert_valid_var.character",
        "assert_valid_var.default",
        "assert_valid_var.factor",
        "assert_valid_var.logical",
        "assert_valid_var.numeric",
        "assert_valid_var.POSIXct"
      ]
    },
    {
      "page": "assert_valid_var_pair",
      "title": "Check variables are of same levels",
      "topics": [
        "assert_valid_var_pair"
      ]
    },
    {
      "page": "assert_valid_variable",
      "title": "Check variables in a data frame are valid character or factor.",
      "topics": [
        "assert_valid_variable"
      ]
    },
    {
      "page": "cfbt01",
      "title": "'CFBT01' Change from Baseline By Visit Table.",
      "topics": [
        "cfbt01",
        "cfbt01_main",
        "cfbt01_post",
        "cfbt01_pre"
      ]
    },
    {
      "page": "chevron_tlg-class",
      "title": "'chevron_tlg' class",
      "topics": [
        ".chevron_g",
        ".chevron_l",
        ".chevron_simple",
        ".chevron_t",
        ".chevron_tlg",
        "chevron_g",
        "chevron_g-class",
        "chevron_graph",
        "chevron_l",
        "chevron_l-class",
        "chevron_listing",
        "chevron_simple",
        "chevron_simple-class",
        "chevron_t",
        "chevron_t-class",
        "chevron_table",
        "chevron_tlg-class"
      ]
    },
    {
      "page": "cml02a_gl",
      "title": "'CML02A_GL' Listing 1 (Default) Concomitant Medication Class Level 2, Preferred Name, and Investigator-Specified Terms.",
      "topics": [
        "cml02a_gl",
        "cml02a_gl_main",
        "cml02a_gl_pre"
      ]
    },
    {
      "page": "cmt01a",
      "title": "'CMT01A' Concomitant Medication by Medication Class and Preferred Name.",
      "topics": [
        "cmt01a",
        "cmt01a_main",
        "cmt01a_post",
        "cmt01a_pre",
        "cmt01_label"
      ]
    },
    {
      "page": "cmt02_pt",
      "title": "'CMT02_PT' Table 1 (Default) Concomitant Medications by Preferred Name.",
      "topics": [
        "cmt02_pt",
        "cmt02_pt_main",
        "cmt02_pt_post",
        "cmt02_pt_pre"
      ]
    },
    {
      "page": "convert_to_month",
      "title": "Helper function to convert to months if needed",
      "topics": [
        "convert_to_month"
      ]
    },
    {
      "page": "coxt01",
      "title": "'COXT01' (Default) Cox Regression Model Table.",
      "topics": [
        "coxt01",
        "coxt01_main",
        "coxt01_post",
        "coxt01_pre"
      ]
    },
    {
      "page": "coxt02",
      "title": "'COXT02' Multi-Variable Cox Regression Model Table.",
      "topics": [
        "coxt02",
        "coxt02_main"
      ]
    },
    {
      "page": "create_id_listings",
      "title": "Concatenate Site and Subject ID",
      "topics": [
        "create_id_listings"
      ]
    },
    {
      "page": "ctcv4_dir",
      "title": "CTC version 4 Grade Direction Data",
      "topics": [
        "ctcv4_dir"
      ]
    },
    {
      "page": "ctcv5_dir",
      "title": "CTC version 5 Grade Direction Data",
      "topics": [
        "ctcv5_dir"
      ]
    },
    {
      "page": "dataset",
      "title": "Data Set",
      "topics": [
        "dataset",
        "dataset,chevron_tlg-method",
        "dataset<-",
        "dataset<-,chevron_tlg-method"
      ]
    },
    {
      "page": "dmt01",
      "title": "'DMT01' Table 1 (Default) Demographics and Baseline Characteristics Table 1.",
      "topics": [
        "dmt01",
        "dmt01_main",
        "dmt01_post",
        "dmt01_pre"
      ]
    },
    {
      "page": "dose_change_rule",
      "title": "Dose Change Rule",
      "topics": [
        "dose_change_rule"
      ]
    },
    {
      "page": "dst01",
      "title": "DST01 Table 1 (Default) Patient Disposition Table 1.",
      "topics": [
        "dst01",
        "dst01_main",
        "dst01_post",
        "dst01_pre"
      ]
    },
    {
      "page": "dtht01",
      "title": "'DTHT01' Table 1 (Default) Death Table.",
      "topics": [
        "dtht01",
        "dtht01_main",
        "dtht01_post",
        "dtht01_pre"
      ]
    },
    {
      "page": "dummy_template",
      "title": "Dummy template.",
      "topics": [
        "dummy_template"
      ]
    },
    {
      "page": "egt01",
      "title": "'EGT01' ECG Parameters and Change from Baseline By Visit Table.",
      "topics": [
        "egt01",
        "egt01_main",
        "egt01_pre"
      ]
    },
    {
      "page": "egt02_1",
      "title": "'EGT02' ECG Abnormalities Table.",
      "topics": [
        "egt02_1",
        "egt02_1_main",
        "egt02_post",
        "egt02_pre"
      ]
    },
    {
      "page": "egt02_2",
      "title": "'EGT02_2' ECG Abnormalities Table.",
      "topics": [
        "egt02_2",
        "egt02_2_main"
      ]
    },
    {
      "page": "egt03",
      "title": "'EGT03' Shift Table of ECG Interval Data - Baseline versus Minimum or Maximum Post-Baseline.",
      "topics": [
        "egt03",
        "egt03_main",
        "egt03_post",
        "egt03_pre"
      ]
    },
    {
      "page": "egt05_qtcat",
      "title": "'EGT05_QTCAT' ECG Actual Values and Changes from Baseline by Visit Table.",
      "topics": [
        "egt05_qtcat",
        "egt05_qtcat_main",
        "egt05_qtcat_post",
        "egt05_qtcat_pre"
      ]
    },
    {
      "page": "empty_rule",
      "title": "Empty rule",
      "topics": [
        "empty_rule"
      ]
    },
    {
      "page": "ext01",
      "title": "'EXT01' Exposure Summary Table.",
      "topics": [
        "ext01",
        "ext01_main",
        "ext01_post",
        "ext01_pre"
      ]
    },
    {
      "page": "format_date",
      "title": "Formatting of date",
      "topics": [
        "format_date"
      ]
    },
    {
      "page": "fstg01",
      "title": "'FSTG01' Subgroup Analysis of Best Overall Response.",
      "topics": [
        "fstg01",
        "fstg01_main",
        "fstg01_pre"
      ]
    },
    {
      "page": "fstg02",
      "title": "'FSTG02' Subgroup Analysis of Survival Duration.",
      "topics": [
        "fstg02",
        "fstg02_main",
        "fstg02_pre"
      ]
    },
    {
      "page": "gen_args",
      "title": "General Argument Name Convention",
      "topics": [
        "gen_args"
      ]
    },
    {
      "page": "get_grade_rule",
      "title": "Get grade rule",
      "topics": [
        "get_grade_rule"
      ]
    },
    {
      "page": "get_section_div",
      "title": "Get Section dividers",
      "topics": [
        "get_section_div"
      ]
    },
    {
      "page": "gg_list",
      "title": "List of 'gg' object",
      "topics": [
        "gg_list"
      ]
    },
    {
      "page": "gg_theme_chevron",
      "title": "Theme for Chevron Plot",
      "topics": [
        "gg_theme_chevron"
      ]
    },
    {
      "page": "grob_list",
      "title": "List of 'grob' object",
      "topics": [
        "grob_list"
      ]
    },
    {
      "page": "h_format_dec",
      "title": "Decimal formatting",
      "topics": [
        "h_format_dec"
      ]
    },
    {
      "page": "kmg01",
      "title": "'KMG01' Kaplan-Meier Plot 1.",
      "topics": [
        "kmg01",
        "kmg01_main",
        "kmg01_pre"
      ]
    },
    {
      "page": "lbt01",
      "title": "'LBT01' Lab Results and Change from Baseline by Visit Table.",
      "topics": [
        "lab_paramcd_precision",
        "lbt01",
        "lbt01_main",
        "lbt01_pre"
      ]
    },
    {
      "page": "lbt04",
      "title": "'LBT04' Laboratory Abnormalities Not Present at Baseline Table.",
      "topics": [
        "lbt04",
        "lbt04_main",
        "lbt04_post",
        "lbt04_pre"
      ]
    },
    {
      "page": "lbt05",
      "title": "'LBT05' Table 1 (Default) Laboratory Abnormalities with Single and Replicated Marked.",
      "topics": [
        "lab_paramcd_abn_dir",
        "lbt05",
        "lbt05_main",
        "lbt05_post",
        "lbt05_pre"
      ]
    },
    {
      "page": "lbt06",
      "title": "'LBT06' Table 1 (Default) Laboratory Abnormalities by Visit and Baseline Status Table 1.",
      "topics": [
        "lbt06",
        "lbt06_main",
        "lbt06_post",
        "lbt06_pre"
      ]
    },
    {
      "page": "lbt07",
      "title": "'LBT07' Table 1 (Default) Laboratory Test Results and Change from Baseline by Visit.",
      "topics": [
        "lbt07",
        "lbt07_main",
        "lbt07_post",
        "lbt07_pre"
      ]
    },
    {
      "page": "lbt14",
      "title": "'LBT14' Laboratory Test Results Shift Table – Highest 'NCI-CTCAE' Grade Post-Baseline by Baseline Grade (Low or High Direction).",
      "topics": [
        "lbt14",
        "lbt14_main",
        "lbt14_post",
        "lbt14_pre"
      ]
    },
    {
      "page": "lbt15",
      "title": "'LBT15' Laboratory Test Shifts to 'NCI-CTCAE' Grade 3-4 Post-Baseline Table.",
      "topics": [
        "lbt15",
        "lbt15_pre"
      ]
    },
    {
      "page": "listing_format_chevron",
      "title": "Format for Chevron Listings",
      "topics": [
        "listing_format_chevron"
      ]
    },
    {
      "page": "lvls",
      "title": "Obtain levels from vector",
      "topics": [
        "lvls"
      ]
    },
    {
      "page": "main",
      "title": "Main",
      "topics": [
        "main",
        "main,chevron_tlg-method",
        "main<-",
        "main<-,chevron_tlg-method"
      ]
    },
    {
      "page": "mht01",
      "title": "'MHT01' Medical History Table.",
      "topics": [
        "mht01",
        "mht01_label",
        "mht01_main",
        "mht01_post",
        "mht01_pre"
      ]
    },
    {
      "page": "missing_rule",
      "title": "Missing rule",
      "topics": [
        "missing_rule"
      ]
    },
    {
      "page": "mla_dir",
      "title": "MLA Grade Direction Data",
      "topics": [
        "mla_dir"
      ]
    },
    {
      "page": "mng01",
      "title": "'MNG01' Mean Plot Graph.",
      "topics": [
        "mng01",
        "mng01_main",
        "mng01_pre"
      ]
    },
    {
      "page": "nocoding",
      "title": "No Coding Available rule",
      "topics": [
        "nocoding"
      ]
    },
    {
      "page": "outcome_rule",
      "title": "Outcome Rule",
      "topics": [
        "outcome_rule"
      ]
    },
    {
      "page": "pdt01",
      "title": "'pdt01' Major Protocol Deviations Table.",
      "topics": [
        "pdt01",
        "pdt01_main",
        "pdt01_post",
        "pdt01_pre"
      ]
    },
    {
      "page": "pdt02",
      "title": "'pdt02' Major Protocol Deviations Related to Epidemic/Pandemic Table.",
      "topics": [
        "pdt02",
        "pdt02_main",
        "pdt02_post",
        "pdt02_pre"
      ]
    },
    {
      "page": "postprocess",
      "title": "Post process",
      "topics": [
        "postprocess",
        "postprocess,chevron_tlg-method",
        "postprocess<-",
        "postprocess<-,chevron_tlg-method"
      ]
    },
    {
      "page": "preprocess",
      "title": "Pre process",
      "topics": [
        "preprocess",
        "preprocess,chevron_tlg-method",
        "preprocess<-",
        "preprocess<-,chevron_tlg-method"
      ]
    },
    {
      "page": "report_null",
      "title": "Creates 'NULL' Report",
      "topics": [
        "report_null",
        "report_null,ANY-method",
        "report_null,list-method",
        "report_null,listing_df-method",
        "report_null,NULL-method",
        "report_null,VTableTree-method",
        "standard_null_report"
      ]
    },
    {
      "page": "rmpt01",
      "title": "'RMPT01'Duration of Exposure for Risk Management Plan Table.",
      "topics": [
        "rmpt01",
        "rmpt01_main",
        "rmpt01_post",
        "rmpt01_pre"
      ]
    },
    {
      "page": "rmpt03",
      "title": "'rmpt03'Duration of Exposure for Risk Management Plan Table.",
      "topics": [
        "rmpt03",
        "rmpt03_main",
        "rmpt03_pre"
      ]
    },
    {
      "page": "rmpt04",
      "title": "'RMPT04'Extent of Exposure by Ethnic Origin for Risk Management Plan Table.",
      "topics": [
        "rmpt04",
        "rmpt04_main",
        "rmpt04_pre"
      ]
    },
    {
      "page": "rmpt05",
      "title": "'RMPT05' Extent of Exposure by Race for Risk Management Plan Table.",
      "topics": [
        "rmpt05",
        "rmpt05_main",
        "rmpt05_pre"
      ]
    },
    {
      "page": "rmpt06",
      "title": "'RMPT06' Table 1 (Default) Seriousness, Outcomes, Severity, Frequency with 95% CI for Risk Management Plan.",
      "topics": [
        "rmpt06",
        "rmpt06_main",
        "rmpt06_post",
        "rmpt06_pre"
      ]
    },
    {
      "page": "rspt01",
      "title": "'RSPT01' Binary Outcomes Summary.",
      "topics": [
        "rspt01",
        "rspt01_main",
        "rspt01_post",
        "rspt01_pre"
      ]
    },
    {
      "page": "run",
      "title": "Run the TLG-generating pipeline",
      "topics": [
        "run",
        "run,chevron_tlg-method"
      ]
    },
    {
      "page": "script",
      "title": "Create Script for 'TLG' Generation",
      "topics": [
        "script",
        "script_funs",
        "script_funs,chevron_simple-method",
        "script_funs,chevron_tlg-method"
      ]
    },
    {
      "page": "set_section_div",
      "title": "Set Section Dividers",
      "topics": [
        "set_section_div"
      ]
    },
    {
      "page": "smart_prune",
      "title": "Prune table up to an 'ElementaryTable'",
      "topics": [
        "smart_prune"
      ]
    },
    {
      "page": "std_postprocessing",
      "title": "Standard Post Processing",
      "topics": [
        "std_postprocessing"
      ]
    },
    {
      "page": "syn_data",
      "title": "Example 'adam' Synthetic Data",
      "topics": [
        "syn_data"
      ]
    },
    {
      "page": "ttet01",
      "title": "'TTET01' Binary Outcomes Summary.",
      "topics": [
        "ttet01",
        "ttet01_main",
        "ttet01_post",
        "ttet01_pre"
      ]
    },
    {
      "page": "var_labels_for",
      "title": "Retrieve labels for certain variables",
      "topics": [
        "var_labels_for"
      ]
    },
    {
      "page": "vst01",
      "title": "'VST01' Vital Sign Results and change from Baseline By Visit Table.",
      "topics": [
        "vst01",
        "vst01_main",
        "vst01_pre"
      ]
    },
    {
      "page": "vst02_1",
      "title": "'VST02' Vital Sign Abnormalities Table.",
      "topics": [
        "vst02_1",
        "vst02_1_main",
        "vst02_post",
        "vst02_pre"
      ]
    },
    {
      "page": "vst02_2",
      "title": "'VST02' Vital Sign Abnormalities Table.",
      "topics": [
        "vst02_2",
        "vst02_2_main"
      ]
    },
    {
      "page": "yes_no_rule",
      "title": "Yes/No rule in title case",
      "topics": [
        "yes_no_rule"
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    "estimability",
    "farver",
    "fastmap",
    "forcats",
    "forecast",
    "formatters",
    "Formula",
    "fracdiff",
    "generics",
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    "glue",
    "gridExtra",
    "gtable",
    "htmltools",
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    "nestcolor",
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    "nnet",
    "numDeriv",
    "pbkrtest",
    "pillar",
    "pkgconfig",
    "purrr",
    "quantreg",
    "R6",
    "rbibutils",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "Rdpack",
    "reformulas",
    "rlang",
    "rlistings",
    "rtables",
    "S7",
    "scales",
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    "stringi",
    "stringr",
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    "tern",
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    "timeDate",
    "urca",
    "utf8",
    "vctrs",
    "viridisLite",
    "withr",
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    "zoo"
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  "_vignettes": [
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      "source": "chevron_catalog.rmd",
      "filename": "chevron_catalog.html",
      "title": "Chevron Catalog",
      "engine": "knitr::rmarkdown",
      "headings": [
        "GENERAL",
        "General Concepts",
        "1. Input dataset and dataset names",
        "2. Expected variables in input analysis dataset",
        "3. Character vs Factor",
        "4. Testing the codes for plot generation",
        "General Control Arguments",
        "1. lbl_overall: Column of Total",
        "2. Column counts: N=xxx",
        "TABLES",
        "Safety Summary (AET01)",
        "1. Safety Summary",
        "2. Safety Summary with Modified Rows",
        "Safety Summary (Adverse Events of Special Interest) (AET01_AESI)",
        "1. Safety Summary (Adverse Events of Special Interest)",
        "2. Safety Summary (Adverse Events of Special Interest) (optional lines)",
        "3. Safety Summary (Adverse Events of Special Interest) (for studies with multiple drugs)",
        "Adverse Events (AET02)",
        "1. Adverse Events",
        "2. Adverse Events (with High-level Term)",
        "3. Adverse Events (Preferred Terms only)",
        "Adverse Events by Greatest Intensity(AET03)",
        "1. Adverse Events by Greatest Intensity",
        "Adverse Events by Highest NCI CTCAE Grade (AET04)",
        "1. Adverse Events by Highest NCI CTCAE Grade",
        "2. Adverse Events by Highest NCI CTCAE Grade (Fill in of Grades)",
        "3. Adverse Events by Highest NCI CTCAE Grade with modified grouping of grade",
        "Adverse Event Rate Adjusted for Patient-Years at Risk - First Occurrence (AET05)",
        "1. Adverse Event Rate Adjusted for Patient-Years at Risk - First Occurrence",
        "2. Adverse Event Rate Adjusted for Patient-Years at Risk - First Occurrence (setting type of confidence interval)",
        "Adverse Event Rate Adjusted for Patient-Years at Risk - All Occurrences (AET05_ALL)",
        "1. Adverse Event Rate Adjusted for Patient-Years at Risk - All Occurrences",
        "2. Adverse Event Rate Adjusted for Patient-Years at Risk - All Occurrences (setting type of confidence interval)",
        "Most Common (>=5%) Adverse Events (AET10)",
        "1. Most Common (>=5%) Adverse Events",
        "2. Most Common (>=8%) Adverse Events (setting threshold)",
        "Absolute Value and Change from Baseline by Visit (CFBT01)",
        "1. Absolute Value and Change from Baseline by Visit",
        "2. Absolute Value and Change from Baseline by Visit without Screening",
        "3. Absolute Value by Visit",
        "Concomitant Medications by Medication Class and Preferred Name (CMT01A)",
        "1. Concomitant Medications by Medication Class and Preferred Name",
        "2. Concomitant Medications by Medication Class and Preferred Name (changing ATC class level)",
        "3. Concomitant Medications by Medication Class and Preferred Name (classes sorted by frequency)",
        "4. Concomitant Medications by Medication Class and Preferred Name (total number of treatments per medication class suppressed)",
        "Concomitant Medications by Preferred Name (CMT02_PT)",
        "1. Concomitant Medications by Preferred Name",
        "Cox Regression (COXT01)",
        "1. Cox Regression",
        "2. Cox Regression (with interaction term)",
        "3. Cox Regression (specifying covariates)",
        "4. Cox Regression (setting strata, ties, and alpha level)",
        "Multi-variable Cox Regression (COXT02)",
        "1. Multi-variable Cox Regression",
        "2. Multi-variable Cox Regression (specifying covariates)",
        "3. Multi-variable Cox Regression (setting strata, ties, and alpha level)",
        "Demographics and Baseline Characteristics (DMT01)",
        "1. Demographics and Baseline Characteristics with All Patients",
        "2. Demographics and Baseline Characteristics without All Patients",
        "3. Demographics and Baseline Characteristics with an additional study specific continuous variable",
        "4. Demographics and Baseline Characteristics with an additional study specific categorical variable",
        "5. Demographics and Baseline Characteristics with additional vital signs baseline values from ADVS or ADSUB",
        "Patient Disposition (DST01)",
        "1. Patient Disposition",
        "2. Patient Disposition (with grouping of reasons)",
        "3. Patient Disposition (adding end of treatment status)",
        "4. Patient Disposition (adding details of study ongoing status)",
        "Deaths (DTHT01)",
        "1. Deaths",
        "2. Deaths (adding \"Primary Cause of Death\" details for 'Other' category)",
        "3. Deaths (adding summary by days from last study drug administration)",
        "ECG Results and Change from Baseline by Visit (EGT01)",
        "1. ECG Results and Change from Baseline by Visit",
        "ECG Abnormalities (Regardless of Abnormality at Baseline) (EGT02_1)",
        "1. ECG Abnormalities (Regardless of Abnormality at Baseline)",
        "ECG Abnormalities (Among Subject Without Abnormality at Baseline) (EGT02_2)",
        "1. ECG Abnormalities (Among Subject Without Abnormality at Baseline)",
        "Shift Table of ECG Interval Data - Baseline versus Minimum/Maximum Post-Baseline (EGT03)",
        "1. Shift Table of ECG Interval Data - Baseline versus Minimum Post-Baseline",
        "2. Shift Table of ECG Interval Data - Baseline versus Maximum Post-Baseline",
        "ECG Actual Values and Changes from Baseline by Visit (EGT05_QTCAT)",
        "1. ECG Actual Values and Changes from Baseline by Visit",
        "2. ECG Actual Values and Changes from Baseline by Visit (removing default analyses)",
        "Study Drug Exposure (EXT01)",
        "1. Study Drug Exposure",
        "Laboratory Test Results and Change from Baseline by Visit (LBT01)",
        "1. Laboratory Test Results and Change from Baseline by Visit",
        "2. Laboratory Test Results and Change from Baseline by Visit (customized precision)",
        "Laboratory Abnormalities (LBT04)",
        "1. Laboratory Abnormalities",
        "Laboratory Abnormalities with Single and Replicated Marked (LBT05)",
        "1. Laboratory Abnormalities with Single and Replicated Marked",
        "2. Laboratory Abnormalities with Single and Replicated Marked showing all categories",
        "3. Laboratory Abnormalities with Single and Replicated Marked with study specific MLAs",
        "Laboratory Abnormalities by Visit and Baseline Status (LBT06)",
        "1. Laboratory Abnormalities by Visit and Baseline Status",
        "Laboratory Test Results with Highest NCI CTCAE Grade Post-Baseline (LBT07)",
        "1. Laboratory Test Results with Highest NCI CTCAE Grade Post-Baseline",
        "Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (LBT14)",
        "1. Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (High)",
        "2. Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (Low)",
        "3. Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (High) Without Patients with Missing Baseline",
        "4. Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (Low) with Missing Baseline Considered as Grade 0",
        "4. Laboratory Test Results Shift Table - Highest NCI-CTCAE Grade Post-Baseline by Baseline NCI-CTCAE Grade (with fill in of grades)",
        "Medical History (MHT01)",
        "1. Medical History",
        "2. Medical History showing additional column 'All Patients'",
        "Major Protocol Deviations (PDT01)",
        "1. Major Protocol Deviations",
        "Reasons for Major Protocol Deviations Related to Epidemic/Pandemic (PDT02)",
        "1. Reasons for Major Protocol Deviations Related to Epidemic/Pandemic",
        "Duration of Exposure for Risk Management Plan (RMPT01)",
        "1. Duration of Exposure for Risk Management Plan",
        "Extent of Exposure by Age Group and Gender for Risk Management Plan (RMPT03)",
        "1. Extent of Exposure by Age Group and Gender for Risk Management Plan",
        "Extent of Exposure by Ethnic Origin for Risk Management Plan (RMPT04)",
        "1. Extent of Exposure by Ethnic Origin for Risk Management Plan",
        "Extent of Exposure by Race for Risk Management Plan (RMPT05)",
        "1. Extent of Exposure by Race for Risk Management Plan",
        "Best Overall Response (RSPT01)",
        "1. Best Overall Response",
        "2. Best Overall Response (Ordering of treatment groups)",
        "3. Best Overall Response (selecting sections to display)",
        "4. Best Overall Response (with stratified analysis)",
        "5. Best Overall Response (modifying analysis details like type of confidence interval, alpha level, test for p-value)",
        "6. Best Overall Response (modifying the definition of overall response)",
        "Time-to-event Summary (TTET01)",
        "1. Time-to-event Summary",
        "2. Time-to-event Summary (selecting sections to display)",
        "3. Time-to-event Summary (modifying analysis details like confidence interval type, ties, and alpha level)",
        "4. Time-to-event Summary (with stratified analysis)",
        "5. Time-to-event Summary (modifying time point for the \"survival at xx months\" analysis)",
        "6. Time-to-event Summary (modifying the p-value method for testing hazard ratio)",
        "Vital Signs (VST01)",
        "1. Vital Sign Results and Change from Baseline by Visit",
        "Vital Signs Abnormalities (Regardless of Abnormality at Baseline) (VST02_1)",
        "1. Vital Sign Abnormalities (Regardless of Abnormality at Baseline)",
        "Vital Signs Abnormalities (Among Subject Without Abnormality at Baseline) (VST02_2)",
        "1. Vital Sign Abnormalities (Among Subject Without Abnormality at Baseline)",
        "LISTINGS",
        "Glossary of Adverse Event Preferred Terms and Investigator-Specified Terms (AEL01_NOLLT)",
        "1. Glossary of Adverse Event Preferred Terms and Investigator-Specified Terms",
        "Graphics",
        "Forest Plot for Odds Ratio (FSTG01)",
        "1. Forest Plot for Odds Ratio (with subgroup analysis)",
        "2. Forest Plot for Odds Ratio (with a user-defined confidence level)",
        "3. Forest Plot for Odds Ratio (with p-values and/or different statistics)",
        "4. Forest Plot for Odds Ratio (with user-defined subgroup analysis)",
        "5. Forest Plot for Odds Ratio (with stratified analysis)",
        "6. Forest Plot for Odds Ratio (without proportional sizing of the odds ratio symbol)",
        "Forest Plot for Hazard Ratio (FSTG02)",
        "1. Forest Plot for Hazard Ratio (with subgroup analysis)",
        "2. Forest Plot for Hazard Ratio (with p-values and/or different statistics)",
        "3. Forest Plot for Hazard Ratio (with user-defined subgroup analysis)",
        "4. Forest Plot for Hazard Ratio (with stratified analysis)",
        "5. Forest Plot for Hazard Ratio (without proportional sizing of the hazard ratio symbol)",
        "Kaplan-Meier Plot (KMG01)",
        "1. Kaplan-Meier Plot (without comparative statistics)",
        "2. Kaplan-Meier Plot (with comparative statistics)",
        "3. Kaplan-Meier Plot (without censoring marks)",
        "4. Kaplan-Meier Plot (without estimation of median survival time)",
        "5. Kaplan-Meier Plot (with statistical annotation of either median or min of survival time)",
        "6. Kaplan-Meier Plot (without the table of patients at risk)",
        "Mean Plot (MNG01)",
        "1. Plot of Mean and Confidence Interval (with Table Section)",
        "2. Plot of Mean and Confidence Interval of Change from Baseline of Vital Signs",
        "3. Plot of Mean (+/-SD) (Changing the Statistics)",
        "4. Plot of Mean and Confidence Interval (Modify Alpha Level)",
        "5. Plot of Mean and Confidence Interval （With Number of Patients Only)",
        "6. Plot of Mean and Confidence Interval (without Table Section)"
      ],
      "created": "2023-07-05 14:14:30",
      "modified": "2024-10-28 12:26:52",
      "commits": 13
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    {
      "source": "chevron.Rmd",
      "filename": "chevron.html",
      "title": "Introduction to Chevron",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "TLG-functions",
        "preprocessing",
        "postprocessing",
        "Example AET02",
        "chevron_tlg object customization",
        "Custom chevron_tlg object creation"
      ],
      "created": "2021-08-18 13:31:01",
      "modified": "2023-12-04 08:34:47",
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    {
      "source": "script_generator.Rmd",
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      "title": "Script_Generator",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Using a chevron-defined object",
        "With a modified chevron object"
      ],
      "created": "2023-03-14 03:26:33",
      "modified": "2023-12-04 08:34:47",
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