Type: Package
Package: simIDM
Title: Simulating Oncology Trials using an Illness-Death Model
Version: 0.1.0
Authors@R: c(
    person("Alexandra", "Erdmann", , "alexandra.erdmann@uni-ulm.de", role = c("aut", "cre")),
    person("Kaspar", "Rufibach", , "kaspar.rufibach@roche.com", role = "aut"),
    person("Holger", "Löwe", , "hbj.loewe@gmail.com", role = "aut"),
    person("Daniel", "Sabanés Bové", , "daniel.sabanes_bove@roche.com", role = "aut"),
    person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")),
    person("University of Ulm", role = c("cph", "fnd"))
  )
Description: Based on the illness-death model a large number of
        clinical trials with oncology endpoints progression-free
        survival (PFS) and overall survival (OS) can be simulated, see
        Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>.
        The simulation set-up allows for random and event-driven
        censoring, an arbitrary number of treatment arms, staggered
        study entry and drop-out.  Exponentially, Weibull and piecewise
        exponentially distributed survival times can be generated. The
        correlation between PFS and OS can be calculated.
License: Apache License 2.0
URL: https://github.com/insightsengineering/simIDM/
BugReports: https://github.com/insightsengineering/simIDM/issues
Depends: R (>= 3.6)
Imports: checkmate, furrr, future, mstate, parallelly, stats, survival
Suggests: coxphw, knitr, mvna, prodlim, rmarkdown, rpact, testthat (>=
        3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Repository: https://insightsengineering.r-universe.dev
Date/Publication: 2023-12-11 09:17:38 UTC
RemoteUrl: https://github.com/insightsengineering/simIDM
RemoteRef: v0.1.0
RemoteSha: a88375167c51fc059096d2289060888a86a68249
NeedsCompilation: no
Packaged: 2026-05-27 08:38:47 UTC; root
Author: Alexandra Erdmann [aut, cre],
  Kaspar Rufibach [aut],
  Holger Löwe [aut],
  Daniel Sabanés Bové [aut],
  F. Hoffmann-La Roche AG [cph, fnd],
  University of Ulm [cph, fnd]
Maintainer: Alexandra Erdmann <alexandra.erdmann@uni-ulm.de>