Changes in version 0.1.0 (2023-12-11) New Features - estimateParams estimates parameters of exponential and Weibull transition hazards using maximum likelihood for a given data set after using prepareData. - corTrans calculates the correlation between PFS and OS for a given set of transition hazards, and corPFSOS estimates this correlation for a given data set, optionally with a bootstrap based confidence interval. Bug Fixes - ExpSurvOS now returns 0 instead of NaN for large values of t. - WeibSurvOS now does not return an error for large values of t. - PWCSurvOS now does not return an error for large values of t. It also no longer returns values larger than 1. It is significantly faster, based on a closed form calculation instead of numerical integration. - getSimulatedData now also works when there are no transitions from progression to death, similarly for getOneClinicalTrial (which now warns if there are no such transitions at all). Miscellaneous - PwcOSInt, integrateVector, WeibOSInteg are no longer exported, and only used internally. - Renamed piecewise constant hazards function to getPWCHazard (previously getPCWHazard). Changes in version 0.0.5 (2023-01-27) - First CRAN version of the package. - The package simulates illness-death models with constant, Weibull or piecewise constant transition hazards. New Features - Exponentially, Weibull and piecewise exponentially distributed survival times. - Random censoring and event-driven censoring after a pre-specified number of PFS or OS events. - Arbitrary number of treatment arms and flexible randomization ratio. - Staggered study entry. - Derivation of PFS and OS survival functions from transition hazards.